Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[C-kit, NPM1 and FLT3 gene mutation patterns and their prognostic significance in 656 Chinese patients with acute myeloid leukemia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 2012

Ding Zi-xuan, Shen Hong-jie, Miao Jing-cheng, Chen Su-ning, Qiu Qiao-cheng, Qi Xiao-fei, Jin Zheng-ming, Wu De-pei, He Jun

Abstract excerpt

OBJECTIVE: To evaluate the prevalence and distribution of C-kit, NPM1 and FLT3 gene mutations in patients with acute myeloid leukemia (AML), and to analyze the relationship between the gene mutations and their prognosis. METHODS: Mutations in exon 8 and 17 of C-kit gene, exon 12 of NPM1 gene, exon 20 of FLT3-TKD gene, and exon 14/15 of FLT3-ITD gene were detected by direct sequencing. Clinical data was collected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Prognosis

Share to Proto-Oncogene Proteins c-kit

Source

Identifiers

PMID: 23384905

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[C-kit, NPM1 and FLT3 gene mutation patterns and their prognostic significance in 656 Chinese patients with acute myeloid leukemia].PMID 23384905Read ↗

[A study of NPM1 and FLT3 gene mutations in acute myeloid leukemia].Semantic proximity Read ↗

[Detection of NPM1, FLT3 and C-KIT mutations in acute myeloid leukemia and their prognostic analysis].Semantic proximity Read ↗

[The immunophenotypic and clinical characteristics of NPM1 mutated acute myeloid leukemia patients].Semantic proximity Read ↗

NPM1, FLT3-ITD, CEBPA, and c-kit mutations in 312 Chinese patients with de novo acute myeloid leukemia.Semantic proximity Read ↗

[Correlation of adult AML Npm1 mutations with prognosis and its relationship with gene mutation of FLT3 and CEBPA].Semantic proximity Read ↗

[Analysis of prognosis of acute myeloid leukemia patients based on genetic mutations].Semantic proximity Read ↗

[Clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation].Semantic proximity Read ↗

[Association of Next Generation Sequencing Based Genotypic Profiling with MICM Characteristics in NPM1 Mutated Acute Myeloid Leukemia].Semantic proximity Read ↗

The prevalence and clinical profiles of FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations in a cohort of patients with de novo acute myeloid leukemia from southwest China.Semantic proximity Read ↗

Analysis of NPM1 gene mutations in Chinese adults with acute myeloid leukemia.Semantic proximity Read ↗

[Immunophenotypic and clinical characteristic analysis of NPM1 mutated acute myeloid leukemia with a normal karyotype].Semantic proximity Read ↗

[The clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.