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[Detection of NPM1, FLT3 and C-KIT mutations in acute myeloid leukemia and their prognostic analysis].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2013

Li Ling, Lyu Xiao-Dong, Mi Rui-Hua, Ding Jing, Chen Lin, Wang Qian, Yin Qing-Song, Hu Jie-Ying, Fan Rui-Hua, Wei Xu-Dong

Abstract excerpt

This study was aimed to evaluate the frequencies and prognostic significance of the nucleophosmin 1 (NPM1) mutation, the fms-like tyrosine kinase 3 (FLT3) mutation and c-KIT mutation in acute myeloid leukemia (AML) and to explore their relevance to clinical characteristics, cytogenetics and survival. Genomic DNA from 78 newly diagnosed AML from August 2010 to October 2012 was screened by PCR and sequencing or...

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Identifiers

PMID: 23815906
DOI: 10.7534/j.issn.1009-2137.2013.03.013

Genes

FLT3
KIT
NPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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