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Article

Rsf-1, a chromatin remodelling protein, interacts with cyclin E1 and promotes tumour development.

The Journal of pathology - 1 Mar 2013

Sheu Jim Jinn-Chyuan, Choi Jung Hye, Guan Bin, Tsai Fuu-Jen, Hua Chun-Hung, Lai Ming-Tsung, Wang Tian-Li, Shih Ie-Ming

Abstract excerpt

Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma. Our previous studies demonstrated requirement of Rsf-1 for cell survival in cancer cells, which contributed to tumour progression; however, its role in tumourigenesis has not yet been elucidated. In this study, we co-immunoprecipitated proteins with Rsf-1...

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Topics

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Share to Cell Cycle
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase 2

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Share to Cystadenocarcinoma, Serous

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Source

Open in PubMed Open full text

Identifiers

PMID: 23378270
DOI: 10.1002/path.4147
PMCID: PMC4353404

Genes

RSF1
CCNE1
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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