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Article

Significance of E2F-1 overexpression in epithelial ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Suh D S, Yoon M S, Choi K U, Kim J Y

Abstract excerpt

E2F-1 is a downstream regulator of the Rb pathway and is a transcription factor that plays a key role in the control of cell cycle progression. Deregulation of E2F-1 expression and Rb pathway is involved in carcinogenesis. The aim of this study was to evaluate E2F-1 expression and Rb pathway alteration and to elucidate their correlation with clinical and pathologic parameters in epithelial ovarian cancer (EOC)....

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Source

Identifiers

PMID: 17692085
DOI: 10.1111/j.1525-1438.2007.01044.x

Genes

CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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