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Article

The TBC1D1 gene: structure, function, and association with obesity and related traits.

Vitamins and hormones - 1 Jan 2013

Fontanesi Luca, Bertolini Francesca

Abstract excerpt

This review summarizes what is currently known on the TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (TBC1D1) gene and gives an overview of its links with human obesity and related traits, taking also information from other animals. Several studies indicated that TBC1D1 contributes to the development of obesity by regulating skeletal muscle insulin sensitivity. A polymorphic site (p.R125W) in the human...

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Identifiers

PMID: 23374713
DOI: 10.1016/B978-0-12-407766-9.00004-3

Genes

USP6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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