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Article

What model organisms and interactomics can reveal about the genetics of human obesity.

Cellular and molecular life sciences : CMLS - 1 Nov 2012

Williams Michael J, Almén Markus S, Fredriksson Robert, Schiöth Helgi B

Abstract excerpt

Genome-wide association studies have identified a number of genes associated with human body weight. While some of these genes are large fields within obesity research, such as MC4R, POMC, FTO and BDNF, the majority do not have a clearly defined functional role explaining why they may affect body weight. Here, we searched biological databases and discovered 33 additional genes associated with human obesity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22618246
DOI: 10.1007/s00018-012-1022-5
PMCID: PMC11114734

Genes

BDNF
CADM2
DNAJC27
ETV5
FAIM2
FANCL
FTO
GIPR
GNPDA2
HMGA1
HMGCR
KCTD15
MTCH2
MTIF3
NEGR1
NRXN3
NUDT3
POC5
POMC
PRKD1
PTBP2
QPCTL
TMEM18
TUB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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