Article
Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.
PloS one - 1 Jan 2016
Volckmar Anna-Lena, Han Chung Ting, Pütter Carolin, Haas Stefan, Vogel Carla I G, Knoll Nadja, Struve Christoph, Göbel Maria, Haas Katharina, Herrfurth Nikolas, Jarick Ivonne, Grallert Harald, Schürmann Annette, Al-Hasani Hadi, Hebebrand Johannes, Sauer Sascha, Hinney Anke
Abstract excerpt
INTRODUCTION: Genes involved in body weight regulation that were previously investigated in genome-wide association studies (GWAS) and in animal models were target-enriched followed by massive parallel next generation sequencing. METHODS: We enriched and re-sequenced continuous genomic regions comprising FTO, MC4R, TMEM18, SDCCAG8, TKNS, MSRA and TBC1D1 in a screening sample of 196 extremely obese children and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
