Article
Effects of paraoxonase 1 activity and gene polymorphisms on long-term pulmonary complications of sulfur mustard-exposed veterans.
International immunopharmacology - 1 Nov 2013
Taravati Ali, Ardestani Sussan K, Ziaee Abed-Ali, Ghorbani Atefeh, Soroush Mohammad-Reza, Faghihzadeh Soghrat, Kazemi Hadi, Rezaei Abbas, Hoseini Habibollah, Ghazanfari Tooba
Abstract excerpt
Sulfur mustard (SM) is an alkylating agent with prolonged adverse effects. The antioxidant paraoxonase 1 (PON1), an endogenous free radical scavenger, plays a protective role against oxidative stress. The possible roles of oxidative stress in the pathogenesis of SM, together with the antioxidant activity of PON1, are enough to warrant the analysis of PON1 polymorphisms and allelic variants in incapacitated...
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