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Article

Effects of intronic and exonic polymorphisms of paraoxonase 1 (PON1) gene on serum PON1 activity in a Korean population.

Journal of Korean medical science - 1 Jun 2011

Eom Sang-Yong, Kim Yun-Sik, Lee Chung-Jong, Lee Chul-Ho, Kim Yong-Dae, Kim Heon

Abstract excerpt

Paraoxonase 1 (PON1) hydrolyzes a number of toxic organophosphorous compounds and reduces lipid peroxide accumulation, and PON1 genetic polymorphisms in the coding region modulate serum PON1 activity. In this study, we investigated the association between 3 polymorphisms of PON1 located in intron 5 (17899insdelTT and 17974CT) and exon 6 (192QR) and serum PON1 activity. The genetic polymorphisms and serum activity...

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Identifiers

PMID: 21655055
DOI: 10.3346/jkms.2011.26.6.720
PMCID: PMC3102863

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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