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Article

Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation.

Arthritis research & therapy - 29 Jan 2013

Hardy Rowan S, Hülso Claudia, Liu Yingling, Gasparini Sylvia J, Fong-Yee Colette, Tu Jinwen, Stoner Shihani, Stewart Paul M, Raza Karim, Cooper Mark S, Seibel Markus J, Zhou Hong

Abstract excerpt

INTRODUCTION: Fibroblast-like synoviocytes (FLS) play a central role in defining the stromal environment in inflammatory joint diseases. Despite a growing use of FLS isolated from murine inflammatory models, a detailed characterisation of these cells has not been performed. METHODS: In this study, FLS were isolated from inflamed joints of mice expressing both the T cell receptor transgene KRN and the MHC class II...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23363614
DOI: 10.1186/ar4158
PMCID: PMC3672796

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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