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Article

Functional expression of the chemokine receptor CCR7 on fibroblast-like synoviocytes

4 Oct 2008

Abstract excerpt

OBJECTIVES: We have characterized the expression and the function of the chemokine receptor CCR7 on fibroblast-like synoviocytes (FLS) of patients with RA and OA and on dermal fibroblasts. METHODS: FLS were obtained after enzymatic digestion of synovial tissue (ST) of patients with RA and OA undergoing knee replacement surgery and taken into culture for chemokine receptor analysis by RT-PCR, flow cytometry and...

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PMID: 18838387
DOI: 10.1093/rheumatology/ken383

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