Article
A detailed association analysis between the tryptophan hydroxylase 2 (TPH2) gene and autism spectrum disorders in a Japanese population.
Psychiatry research - 30 Apr 2012
Egawa Jun, Watanabe Yuichiro, Nunokawa Ayako, Endo Taro, Kaneko Naoshi, Tamura Ryu, Sugiyama Toshiro, Someya Toshiyuki
Abstract excerpt
We conducted a detailed association analysis between the tryptophan hydroxylase 2 gene and autism spectrum disorders in a Japanese population using 19 markers, including tagging single nucleotide polymorphisms and a novel missense variation, p.R225Q, identified through exon resequencing. However, we failed to obtain supportive evidence for an association.
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