Article
Interlaboratory comparison of IDH mutation detection.
Journal of neuro-oncology - 1 Apr 2013
van den Bent Martin J, Hartmann C, Preusser Matthias, Ströbel Thomas, Dubbink Hendrikus J, Kros Johan M, von Deimling Andreas, Boisselier Blandine, Sanson Marc, Halling Kevin C, Diefes Kristin L, Aldape Kenneth, Giannini Caterina
Abstract excerpt
Isocitrate dehydrogenase (IDH) mutational testing is becoming increasingly important. For this, robust and reliable assays are needed. We tested the variation of results between six laboratories of testing for IDH mutations. Each laboratory received five unstained slides from 31 formalin-fixed paraffin-embedded (FFPE) glioma samples, and followed its own standard IDH diagnostic routine. All laboratories used...
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