A fourth Sp1 site in the human immunodeficiency virus type 1 long terminal repeat is essential for negative-sense transcription.

doi:10.1128/JVI.70.10.6665-6672.1996

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Article

A fourth Sp1 site in the human immunodeficiency virus type 1 long terminal repeat is essential for negative-sense transcription.

Journal of virology - 1 Oct 1996

Peeters A, Lambert P F, Deacon N J

Abstract excerpt

We report the discovery of a fourth Sp1 binding site at the 5' end of the U3 region of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (HIV-1 Sp1 IV), localized to HXB2 nucleotides -433 to -441. This site is shown to bind Sp1 protein specifically in electrophoretic mobility s...

Topics

Antisense Elements (Genetics)
HIV Long Terminal Repeat
HIV-1
Humans
Mutation
Promoter Regions, Genetic
Sequence Analysis
Transcription, Genetic

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