Article
Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms.
BioMed research international - 1 Jan 2015
Shah Sonia, Pirrone Vanessa, Alexaki Aikaterini, Nonnemacher Michael R, Wigdahl Brian
Abstract excerpt
Following human immunodeficiency virus type 1 (HIV-1) integration into host cell DNA, the viral promoter can become transcriptionally silent in the absence of appropriate signals and factors. HIV-1 gene expression is dependent on regulatory elements contained within the long terminal repeat (LTR)...
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