Two strains of SIVmac show differential transactivation mediated by sequences in the promoter.

doi:10.1016/0042-6822(92)90231-d

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Article

Two strains of SIVmac show differential transactivation mediated by sequences in the promoter.

Virology - 1 Dec 1992

Anderson M G, Clements J E

Abstract excerpt

Two infectious molecular clones of simian immunodeficiency virus, SIVmac251 and SIVmac239, have very different in vivo properties, SIVmac239 being much more pathogenic than SIVmac251. To assess whether the in vivo differences between the two viruses would be reflected in transcriptional rates in...

Topics

Base Sequence
Cells, Cultured
Chloramphenicol O-Acetyltransferase
DNA Mutational Analysis
Gene Expression Regulation, Viral
Gene Products, tat
Genetic Variation
Molecular Sequence Data
Promoter Regions, Genetic
RNA, Messenger
Recombinant Proteins
Repetitive Sequences, Nucleic Acid
Simian Immunodeficiency Virus
Structure-Activity Relationship
Transcriptional Activation
Transfection

Source

Open in PubMed

Identifiers

PMID: 1448914
DOI: 10.1016/0042-6822(92)90231-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1448914-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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