Article
Two strains of SIVmac show differential transactivation mediated by sequences in the promoter.
Virology - 1 Dec 1992
Anderson M G, Clements J E
Abstract excerpt
Two infectious molecular clones of simian immunodeficiency virus, SIVmac251 and SIVmac239, have very different in vivo properties, SIVmac239 being much more pathogenic than SIVmac251. To assess whether the in vivo differences between the two viruses would be reflected in transcriptional rates in vitro, transcriptional activity in the presence of the transactivation protein tat was analyzed by transient...
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