Article
Cox-2 gene variants in migraine.
Gene - 15 Apr 2013
Dasdemir Selcuk, Cetinkaya Yilmaz, Gencer Mehmet, Ozkok Elif, Aydin Makbule, Cakmakoglu Bedia
Abstract excerpt
PURPOSE: Migraine is a multifactorial and complex disorder, and any clear diagnostic marker to assess the status of the migraineurs has not been established, yet. Nonsteroidal anti-inflammatory drugs reduce production of prostanoids including PGE2 by inhibiting COX-1 and/or COX-2, and thereby suppress inflammatory pain in patients suffering from rheumatoid arthritis, osteoarthritis, and migraine. Thus, COX-2...
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