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COX-2-8473 T>C gene variant (rs5275) is associated with depression and nausea in migraineurs by increasing inflammation through MyD88/MAP2K3/COX-2

2023-12-23

Abstract excerpt

<title>Abstract</title> <p>Migraine is a complicated neurological disorder. Cyclooxygenase-2 (COX-2) is a crucial enzyme involved in the pain response and inflammation. COX-2 modulation is necessary in migraine therapy. We hypothesized that the COX-2-8473 T > C (rs5275) gene variant might be related to migraine, depression, and nausea. In this case-control research, 100 migraineurs and 100 control cases in Busheh...

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Literature Corpus work
77b4c26f-27d8-50a5-9791-ec3f91c8004f
DOI
10.21203/rs.3.rs-3781916/v1
Open publication

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COX-2-8473 T&gt;C gene variant (rs5275) is associated with depression and nausea in migraineurs by increasing inflammation through MyD88/MAP2K3/COX-2DOI 10.21203/rs.3.rs-3781916/v1
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