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Article

Genetic predisposition of TNFα gene polymorphism in South-Indian Migraineurs and meta-analysis.

Frontiers in bioscience (Elite edition) - 20 Dec 2021

Kesavan Pallavi, Satheesh Aiswarya Padmaja, Husain Rehman Syed Rasheed Akram, Veerappan Umamaheshwari, Kannaian Subramaniyan, Ahmed Shiek Ssj, Veerabathiran Ramakrishnan

Abstract excerpt

Migraine (Mg) is a multifaceted neurovascular disorder caused by genetic and several environmental etiologies. We have implemented a case-control study of TNFα gene polymorphism in 212 Mg patients and 218 healthy controls utilizing the ARMS-PCR technique, followed by Sanger sequencing. Besides, we have conducted a meta-analysis of different genetic models (five genetic models) to combine and summarize the...

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PMID: 34937310
DOI: 10.52586/E880

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