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Article

Multiple regulatory elements determine adrenocortical expression of steroid 21-hydroxylase.

The Journal of biological chemistry - 15 May 1990

Rice D A, Kronenberg M S, Mouw A R, Aitken L D, Franklin A, Schimmer B P, Parker K L

Abstract excerpt

Steroid 21-hydroxylase (21-OHase) is specifically expressed at high levels in the adrenal cortex, where it is required for the synthesis of mineralocorticoids and glucocorticoids. In this study, we have investigated the regulatory elements in the 21-OHase promoter region which contribute to the expression of this gene in Y1 adrenocortical cells. Eight potential regulatory elements in the 5'-flanking region of the...

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PMID: 2335516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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