Article
Characterization of the promoter of SF-1, an orphan nuclear receptor required for adrenal and gonadal development.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 1997
Woodson K G, Crawford P A, Sadovsky Y, Milbrandt J
Abstract excerpt
Steroidogenic factor 1 (SF-1) is a transcription factor shown to be critical for regulation of adrenal and gonadal development and function. To dissect the mechanisms that direct expression of this regulator, we have studied the promoter of the SF-1 gene and have identified cis-acting elements that recognize a basic-helix-loop-helix transcription factor; the CAAT binding factor; and Sp1. We demonstrate in Y1...
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