Article
Characterization of the promoter of SF-1, an orphan nuclear receptor required for adrenal and gonadal development.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 1997
Woodson K G, Crawford P A, Sadovsky Y, Milbrandt J
Abstract excerpt
Steroidogenic factor 1 (SF-1) is a transcription factor shown to be critical for regulation of adrenal and gonadal development and function. To dissect the mechanisms that direct expression of this regulator, we have studied the promoter of the SF-1 gene and have identified cis-acting elements th...
Topics
- Adrenal Cortex
- Animals
- Base Sequence
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- Cells, Cultured
- DNA-Binding Proteins
- Fushi Tarazu Transcription Factors
- Homeodomain Proteins
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Receptors, Cytoplasmic and Nuclear
- Regulatory Sequences, Nucleic Acid
- Sequence Analysis, DNA