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Article

Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.

Molecular endocrinology (Baltimore, Md.) - 1 Jun 1990

Bogerd A M, Franklin A, Rice D A, Schimmer B P, Parker K L

Abstract excerpt

We have studied the mechanisms that regulate the expression of the mouse gene encoding steroid 11 beta-hydroxylase (11 beta-OHase), a steroidogenic cytochrome P450 enzyme that is expressed only in the adrenal cortex. DNase I footprinting and gel-mobility shift analyses revealed potential regulatory elements at -370 and -310 in the 11 beta-OHase promoter region. To determine the contributions of these elements to...

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PMID: 2233742
DOI: 10.1210/mend-4-6-845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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