Article
Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.
Molecular endocrinology (Baltimore, Md.) - 1 Jun 1990
Bogerd A M, Franklin A, Rice D A, Schimmer B P, Parker K L
Abstract excerpt
We have studied the mechanisms that regulate the expression of the mouse gene encoding steroid 11 beta-hydroxylase (11 beta-OHase), a steroidogenic cytochrome P450 enzyme that is expressed only in the adrenal cortex. DNase I footprinting and gel-mobility shift analyses revealed potential regulato...
Topics
- Adrenal Cortex Neoplasms
- Animals
- Base Sequence
- Gene Expression Regulation, Neoplastic
- Genes, Regulator
- Mice
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Protein Kinase C
