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Article

Difference in transcriptional activity of two homologous CYP21A genes.

Molecular endocrinology (Baltimore, Md.) - 1 Oct 1995

Chang S F, Chung B C

Abstract excerpt

Steroid 21-hydroxylase (CYP21) deficiency is the major cause of congenital adrenal hyperplasia, a common genetic disease due to steroid imbalance. The main cause for the mutation of the CYP21A2 (c21B) gene is conversion of its nucleotide sequence to the neighboring homologous but nonfunctional c21A gene. In this report the transcriptional activities of the c21A and c21B genes have been analyzed. Transient...

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Identifiers

PMID: 8544841
DOI: 10.1210/mend.9.10.8544841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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