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Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?

Human genetics - 1 May 2013

Ganna Andrea, Rivadeneira Fernando, Hofman Albert, Uitterlinden André G, Magnusson Patrik K E, Pedersen Nancy L, Ingelsson Erik, Tiemeier Henning

Abstract excerpt

Twin studies have estimated the heritability of longevity to be approximately 20-30 %. Genome-wide association studies (GWAS) have revealed a large number of determinants of morbidity, but so far, no new polymorphisms have been discovered to be associated with longevity per se in GWAS. We aim to...

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PMID: 23354976
DOI: 10.1007/s00439-013-1267-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23354976-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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