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Streptococcus pneumoniae Folate Biosynthesis Responds to Environmental CO2Levels

26 Jan 2013

Abstract excerpt

Although carbon dioxide (CO2) is known to be essential for Streptococcus pneumoniae growth, it is poorly understood how this respiratory tract pathogen adapts to the large changes in environmental CO2 levels it encounters during transmission, host colonization, and disease. To identify the molecular mechanisms that facilitate pneumococcal growth under CO2-poor conditions, we generated a random S. pneumoniae R6...

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PMID: 23354753
DOI: 10.1128/jb.01942-12

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