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Article

Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1.

Eukaryotic cell - 1 Jan 2006

Mogensen Estelle Geweiss, Janbon Guilhem, Chaloupka James, Steegborn Clemens, Fu Man Shun, Moyrand Frédérique, Klengel Torsten, Pearson David S, Geeves Michael A, Buck Jochen, Levin Lonny R, Mühlschlegel Fritz A

Abstract excerpt

Cryptococcus neoformans, a fungal pathogen of humans, causes fatal meningitis in immunocompromised patients. Its virulence is mainly determined by the elaboration of a polysaccharide capsule surrounding its cell wall. During its life, C. neoformans is confronted with and responds to dramatic variations in CO2 concentrations; one important morphological change triggered by the shift from its natural habitat...

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Identifiers

PMID: 16400172
DOI: 10.1128/EC.5.1.103-111.2006
PMCID: PMC1360268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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