Article
Three functional β-carbonic anhydrases in Pseudomonas aeruginosa PAO1: role in survival in ambient air
1 Jun 2013
Abstract excerpt
Bacterial β-class carbonic anhydrases (CAs) are zinc metalloenzymes catalysing reversible hydration of CO2. They maintain the intracellular balance of CO2/bicarbonate required for biosynthetic reactions and represent a new group of antimicrobial drug targets. Genome sequence analysis of Pseudomonas aeruginosa PAO1, an opportunistic human pathogen causing life threatening infections, identified three genes,...
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