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<i>Cryptococcus neoformans</i> adapts to host CO <sub>2</sub> concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasis

2025-11-29

Abstract excerpt

Cryptococcus neoformans is an environmental pathogen that remodels its cellular physiology to survive within mammals and, in susceptible hosts, cause life-threatening meningoencephalitis. Of the many distinctions between the external environment and mammalian tissues, CO 2 concentration in the host is 2 orders of magnitude higher than in the environment and represent a critical stress for C. neoformans . C. neo...

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Identifiers and source

Literature Corpus work
670bd622-e9c3-5d51-a5ce-9a8ba386fe11
DOI
10.1101/2025.11.28.691145
Open publication

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<i>Cryptococcus neoformans</i> adapts to host CO <sub>2</sub> concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasisDOI 10.1101/2025.11.28.691145
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