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Competence remodels the pneumococcal cell wall providing resistance to fratricide and surface exposing key virulence factors

2022-08-04

Abstract excerpt

Competence development in the human pathogen Streptococcus pneumoniae controls several features such as genetic transformation, biofilm formation and virulence. Competent bacteria produce so called ‘fratricins’ such as CbpD, that kill non-competent siblings by cleaving peptidoglycan (PGN). CbpD is a choline-binding protein (CBP) that binds to phosphorylcholine residues found on wall- and lipoteichoic acids (WTA a...

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Literature Corpus work
d29f1181-a5dd-5ee4-8696-49780c6dd4e4
DOI
10.1101/2022.08.03.502730
Open publication

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Competence remodels the pneumococcal cell wall providing resistance to fratricide and surface exposing key virulence factorsDOI 10.1101/2022.08.03.502730
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