Article
The effects of methionine acquisition and synthesis on Streptococcus pneumoniae growth and virulence.
PloS one - 1 Jan 2013
Basavanna Shilpa, Chimalapati Suneeta, Maqbool Abbas, Rubbo Bruna, Yuste Jose, Wilson Robert J, Hosie Arthur, Ogunniyi Abiodun D, Paton James C, Thomas Gavin, Brown Jeremy S
Abstract excerpt
Bacterial pathogens need to acquire nutrients from the host, but for many nutrients their importance during infection remain poorly understood. We have investigated the importance of methionine acquisition and synthesis for Streptococcus pneumoniae growth and virulence using strains with gene deletions affecting a putative methionine ABC transporter lipoprotein (Sp_0149, metQ) and/or methionine biosynthesis...
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