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Article

MetR is a molecular adaptor for pneumococcal carriage in the healthy upper airway

3 Apr 2021

Abstract excerpt

Streptococcus pneumoniae resides in the human upper airway as a commensal but also causes pneumonia, bacteremia, meningitis, and otitis media. It remains unclear how pneumococci adapt to nutritional conditions of various host niches. We here show that MetR, a LysR family transcriptional regulator, serves as a molecular adaptor for pneumococcal fitness, particularly in the upper airway. The metR mutant of strain...

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PMID: 33811693
DOI: 10.1111/mmi.14724

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