Article
Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo.
PloS one - 1 Jan 2012
Chimalapati Suneeta, Cohen Jonathan M, Camberlein Emilie, MacDonald Nathanael, Durmort Claire, Vernet Thierry, Hermans Peter W M, Mitchell Timothy, Brown Jeremy S
Abstract excerpt
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens. As prolipoproteins are attached to the cell membrane by a single enzyme, prolipoprotein diacylglyceryl transferase (Lgt), deletion of the corresponding gene potentially allows the characterisation of the overall importance of lipoproteins for specific...
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