Article

Methylthioadenosine reduces host inflammatory response by suppressing <i>Salmonella</i> virulence

2018-03-23

Abstract excerpt

In order to deploy virulence factors at appropriate times and locations, microbes must rapidly sense and respond to various metabolite signals. Previously we showed transient elevation of the methionine-derived metabolite methylthioadenosine (MTA) in serum during systemic Salmonella enterica serovar Typhimurium ( S. Typhimurium) infection. Here we explored the functional consequences of increased MTA concentrati...

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Literature Corpus work: 5bd8d6f2-d3db-577e-9ca4-c521d50b4b91
DOI: 10.1101/287052

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