Article
KLF6-SV1 drives breast cancer metastasis and is associated with poor survival.
Science translational medicine - 23 Jan 2013
Hatami Raheleh, Sieuwerts Anieta M, Izadmehr Sudeh, Yao Zhong, Qiao Rui Fang, Papa Luena, Look Maxime P, Smid Marcel, Ohlssen Jessica, Levine Alice C, Germain Doris, Burstein David, Kirschenbaum Alexander, DiFeo Analisa, Foekens John A, Narla Goutham
Abstract excerpt
Metastasis is the major cause of cancer mortality. A more thorough understanding of the mechanisms driving this complex multistep process will aid in the identification and characterization of therapeutically targetable genetic drivers of disease progression. We demonstrate that KLF6-SV1, an onco...
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