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Article

Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1.

Human cell - 30 Oct 2024

Zhang Chenlu, Liu Mengling, Luan Lijuan, Guo Xi, You Yang, Wang Zhiming, Li Wei, Lu Nanhang, Hou Yingyong, Lu Lili, Lu Weiqi, Zhou Yuhong

Abstract excerpt

The methods available for treating metastatic Ewing sarcoma (ES) are inadequate; thus, innovative therapeutic approaches need to be developed. However, the lack of clinically relevant ES models has hindered the discovery of drugs for this disease. In this study, we established and characterized a patient-derived xenograft (PDX) cell line model, which was constructed using tumor tissue from a patient with...

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PMID: 39475964
DOI: 10.1007/s13577-024-01133-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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