Article
Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities.
PloS one - 6 Aug 2010
Bemmo Amandine, Dias Christel, Rose April A N, Russo Caterina, Siegel Peter, Majewski Jacek
Abstract excerpt
BACKGROUND: Breast cancer is the second most frequent type of cancer affecting women. We are increasingly aware that changes in mRNA splicing are associated with various characteristics of cancer. The most deadly aspect of cancer is metastasis, the process by which cancer spreads from the primary tumor to distant organs. However, little is known specifically about the involvement of alternative splicing in the...
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