Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel isoform of ATOH8 promotes the metastasis of breast cancer by regulating RhoC

29 Sept 2020

Abstract excerpt

Metastases are the main cause of cancer-related mortality in breast cancer. Although significant progress has been made in the field of tumor metastasis, the exact molecular mechanisms involved in tumor metastasis are still unclear. Here, we report that ATOH8-V1, a novel isoform of ATOH8, is highly expressed in breast cancer and is a negative prognostic indicator of survival for patients. Forced expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33049034
DOI: 10.1093/jmcb/mjaa050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel isoform of ATOH8 promotes the metastasis of breast cancer by regulating RhoCPMID 33049034Read ↗

In Vivo CRISPR Screens Identify RhoV as a Pro-Metastasis Factor of Triple-Negative Breast CancerSemantic proximity Read ↗

THAP7-AS1 recruits the SWI/SNF to activate EGFR-ELK1 signaling and induce crosstalk between tumor-associated macrophages and breast cancer cellsSemantic proximity Read ↗

Integrative analyses of scRNA-seq and scATAC-seq reveal CXCL14 as a key regulator of lymph node metastasis in breast cancerSemantic proximity Read ↗

ARID1A Mutation in Metastatic Breast Cancer: A Potential Therapeutic TargetSemantic proximity Read ↗

KLF6-SV1 drives breast cancer metastasis and is associated with poor survival.Semantic proximity Read ↗

The long noncoding RNA AATBC promotes breast cancer migration and invasion by interacting with YBX1 and activating the YAP1/Hippo signaling pathwaySemantic proximity Read ↗

ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathwaySemantic proximity Read ↗

Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer.Semantic proximity Read ↗

Role of Metastasis Suppressor KAI1/CD82 in Different CancersSemantic proximity Read ↗

C1orf61 promotes hepatocellular carcinoma metastasis and affects the therapeutic response to sorafenibSemantic proximity Read ↗

Angio-Associated Migratory Cell Protein (AAMP) Regulates the Hippo/YAP Pathway and Mitochondrial Functionality to Drive Osteosarcoma MetastasisSemantic proximity Read ↗

LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.