Article
MAIT cell recognition of MR1 on bacterially infected and uninfected cells.
PloS one - 1 Jan 2013
Young Mary H, U'Ren Lance, Huang Shouxiong, Mallevaey Thierry, Scott-Browne James, Crawford Frances, Lantz Olivier, Hansen Ted H, Kappler John, Marrack Philippa, Gapin Laurent
Abstract excerpt
Mucosal-associated invariant T cells are a unique population of T cells that express a semi-invariant αβ TCR and are restricted by the MHC class I-related molecule MR1. MAIT cells recognize uncharacterized ligand(s) presented by MR1 through the cognate interaction between their TCR and MR1. To un...
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