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Article

MR1-Restricted T Cells Are Unprecedented Cancer Fighters.

Frontiers in immunology - 1 Jan 2020

Vacchini Alessandro, Chancellor Andrew, Spagnuolo Julian, Mori Lucia, De Libero Gennaro

Abstract excerpt

Non-polymorphic MHC class I-related molecule MR1 presents antigenic bacterial metabolites to mucosal-associated invariant T (MAIT) cells and self-antigens to MR1-restricted T (MR1T) cells. Both MR1-restricted T cell populations are readily identified in healthy individuals, with MAIT cells accounting for 1-10% of circulating T cells, while MR1T cells have frequencies comparable to peptide-specific T cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32411144
DOI: 10.3389/fimmu.2020.00751
PMCID: PMC7198878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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