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Article

Insights into Aβ aggregation: a molecular dynamics perspective.

Current topics in medicinal chemistry - 1 Jan 2012

Shea Joan-Emma, Urbanc Brigita

Abstract excerpt

This article reviews recent molecular dynamics simulations of the Alzheimer's amyloid-β protein, the primary component of the amyloid plaques found in the brain of Alzheimer's patients. Different simulation techniques, and their application to the study of monomeric, oligomeric, and fibrillar species is discussed. This review highlights how simulations have acted as an invaluable complement to experiment,...

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Identifiers

PMID: 23339310
DOI: 10.2174/1568026611212220012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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