Article

Dynamics of oligomer populations formed during the aggregation of Alzheimer’s A <i>β</i> 42 peptide

2020-01-11

Abstract excerpt

Oligomeric aggregates populated during the aggregation of the A β 42 peptide have been identified as potent cytotoxins linked to Alzheimer’s disease, but the fundamental molecular pathways that control their dynamics have yet to be elucidated. By developing a general approach combining theory, experiment, and simulation, we reveal in molecular detail the mechanisms of A β 42 oligomer dynamics during amyloid fibr...

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Literature Corpus work: 43bbc503-d740-5adc-9a44-66494c520561
DOI: 10.1101/2020.01.08.897488

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