Article

Different force fields give rise to different amyloid aggregation pathways in molecular dynamics simulations

2020-09-10

Abstract excerpt

The progress towards understanding the molecular basis of Alzheimers’s disease is strongly connected to elucidating the early aggregation events of the amyloid- β (A β ) peptide. Molecular dynamics (MD) simulations provide a viable technique to study the aggregation of A β into oligomers with high spatial and temporal resolution. However, the results of an MD simulation can only be as good as the underlying for...

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Literature Corpus work: b43df6d5-8b20-5671-994d-c7fe2eb766fe
DOI: 10.1101/2020.09.09.290320

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