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Article

HSV, Axonal Transport and Alzheimer‘s Disease:in Vitroandin VivoEvidence for Causal Relationships

1 Sept 2012

Abstract excerpt

HSV, a neurotropic virus, travels within neuronal processes by fast axonal transport. During neuronal infection HSV travels retrograde from the sensory nerve terminus to the neuronal cell body, where it replicates or enters latency. During replication HSV travels anterograde from the cell body to the nerve terminus. Postmortem studies find a high frequency of HSV DNA in the trigeminal ganglia as well as the...

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PMID: 23335944
DOI: 10.2217/fvl.12.81

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