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Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton

23 Feb 2018

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is a neuroinvasive human pathogen that has the ability to infect and replicate within epithelial cells and neurons and establish a life-long latent infection in sensory neurons. HSV-1 depends on the host cellular cytoskeleton for entry, replication, and exit. Therefore, HSV-1 has adapted mechanisms to promote its survival by exploiting the microtubule and actin cytoskeletons to...

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PMID: 29473915
DOI: 10.3390/v10020092

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