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Article

ADAM33's Role in Asthma Pathogenesis: An Overview.

International journal of molecular sciences - 15 Feb 2024

Sleziak Jakub, Gawor Antoni, Błażejewska Marta, Antosz Katarzyna, Gomułka Krzysztof

Abstract excerpt

Asthma is a complex chronic respiratory disease characterized by airway hyperresponsiveness, inflammation, and obstruction. Many genes have been identified as associated with asthma but none with such substantial significance as the ADAM33 gene due to its role in airway remodeling and bronchial hyperresponsiveness. This review summarizes the current knowledge on the genetic and functional aspects of ADAM33 in...

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Identifiers

PMID: 38396994
DOI: 10.3390/ijms25042318
PMCID: PMC10889317

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