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Article

Analysis of family- and population-based samples using multiple linkage disequilibrium mapping.

Annals of human genetics - 1 May 2013

Chiu Yen-Feng, Lee Chun-Yi, Kao Hui-Yi, Pan Wen-Harn, Hsu Fang-Chi

Abstract excerpt

We report two methods for linkage disequilibrium mapping that involve incorporation of covariates through parametric modeling to utilize combined case-parent trios and unrelated case and/or control data. The proposed two combined methods were used to map the disease locus of hypertension in the angiotensin-converting enzyme (ACE) gene with incorporation of ACE activity. The efficiencies in estimating the disease...

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Identifiers

PMID: 23330688
DOI: 10.1111/ahg.12008

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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