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Article

Effects of C4 null alleles and homoduplications on quantitative expression of C4A and C4B.

Clinical and experimental immunology - 1 Apr 1992

Hammond A, Ollier W, Walport M J

Abstract excerpt

The availability of MoAbs now allows the accurate quantification of the individual C4 isotypes, C4A and C4B. Using a sensitive two-site immunoradiometric technique to measure serum levels of C4A and C4B, we studied the relationship between genotype and phenotype and physiological factors affecting C4 expression in 129 fully genotyped healthy subjects. Our results confirm that there is extensive phenotypic overlap...

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Identifiers

PMID: 1563101
DOI: 10.1111/j.1365-2249.1992.tb03057.x
PMCID: PMC1554358

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Source receipt: pubmed, retrieved 7 Sept 2026.

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