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Article

cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells.

Molecular biology of the cell - 1 Mar 2013

Li Donghui, Dammer Eric B, Lucki Natasha C, Sewer Marion B

Abstract excerpt

Diaphanous homologue 1 (DIAPH1) is a Rho effector protein that coordinates cellular dynamics by regulating microfilament and microtubule function. We previously showed that DIAPH1 plays an integral role in regulating the production of cortisol by controlling the rate of mitochondrial movement, by which activation of the adrenocorticotropin (ACTH)/cAMP signaling pathway stimulates mitochondrial trafficking and...

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Source

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Identifiers

PMID: 23325789
DOI: 10.1091/mbc.E12-08-0597
PMCID: PMC3596254

Genes

DIAPH1
OSBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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