Article
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation.
The Journal of cell biology - 16 Jul 2007
Brandt Dominique T, Marion Sabrina, Griffiths Gareth, Watanabe Takashi, Kaibuchi Kozo, Grosse Robert
Abstract excerpt
The Diaphanous-related formin Dia1 nucleates actin polymerization, thereby regulating cell shape and motility. Mechanisms that control the cellular location of Dia1 to spatially define actin polymerization are largely unknown. In this study, we identify the cytoskeletal scaffold protein IQGAP1 as...
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