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Article

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency.

Arthritis research & therapy - 16 Jan 2013

Martin Praxedis, Talabot-Ayer Dominique, Seemayer Christian Alexander, Vigne Solenne, Lamacchia Céline, Rodriguez Emiliana, Finckh Axel, Smith Dirk E, Gabay Cem, Palmer Gaby

Abstract excerpt

INTRODUCTION: Interleukin (IL)-33 is a cytokine of the IL-1 family, which signals through the ST2 receptor. Previous work suggested implication of the IL-33/ST2 axis in the pathogenesis of human and mouse arthritis. Here, we directly investigated the role of endogenous IL-33 in K/BxN serum transfer-induced arthritis by using IL-33 knockout (KO) mice. METHODS: Arthritis was induced by injection of complete K/BxN...

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Identifiers

PMID: 23324173
DOI: 10.1186/ar4143
PMCID: PMC3672723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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